Pathology of the formalin-treated heterograft porcine aortic valve in the mitral position.
نویسنده
چکیده
was performed on two of the failed heterograft valves and three control pig valves. Failure of the heterograft was due to stretching and deformation of the cusps with resultant valvular incompetence. Stretching of the cusp was a result of reduction in the amount of its collagen content. The elastic tissue appeared little altered. A microscopic layer of fibrin thrombus was present on the surface of 8 of the 11 valves. Only 2 of the 11 valves showed invasion of the graft by immunologically competent cells. No valve showed any sign of infection or calcification. The denatured collagen of the heterograft has a low antigenicity and also, unfortunately,
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ورودعنوان ژورنال:
- Thorax
دوره 27 4 شماره
صفحات -
تاریخ انتشار 1972